Anti-FADD antibody (1-208) (STJ11100055) STJ11100055|产品目录|代理商|上海榴莲视频色版下载安装生物科技有限公司

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产品名称：Anti-FADD antibody (1-208) (STJ11100055)
产品型号：STJ11100055
产品厂商：ST john's laboratory
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简单介绍：

Anti-FADD antibody (1-208) (STJ11100055)

详情介绍：

Host:	Rabbit
Applications:	WB/IP
Reactivity:	Human/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-FADD (1-208) is suitable for use in Western Blot and Immunoprecipitation research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IP 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FADD
Gene ID:	8772
Uniprot ID:	FADD_HUMAN
Immunogen Region:	1-208
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-208 of human FADD (NP_003815.1).
Immunogen Sequence:	MDPFLVLLHSVSSSLSSSEL TELKFLCLGRVGKRKLERVQ SGLDLFSMLLEQNDLEPGHT ELLRELLASLRRHDLLRRVD DFEAGAAAGAAPGEEDLCAA FNVICDNVGKDWRRLARQLK VSDTKIDSIEDRYPRNLTER VRESLRIWKNTEKENATVAH LVGALRSCQMNLVADLVQEV QQARDLQNRSGAMSPMSWNS DASTSEAS

Tissue Specificity	Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.
Post Translational Modifications	(Microbial infection) Glycosylated at Arg-117 by enteropathogenic E.coli protein NleB1, C.rodentium protein NleB and S.typhimurium protein Ssek1: arginine GlcNAcylation prevents recruitment of caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors.
Function	Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Protein Name	Fas-Associated Death Domain Protein Fas-Associating Death Domain-Containing Protein Growth-Inhibiting Gene 3 Protein Mediator Of Receptor Induced Toxicity
Database Links	Reactome: R-HSA-140534 Reactome: R-HSA-2562578 Reactome: R-HSA-3371378 Reactome: R-HSA-5213460 Reactome: R-HSA-5218900 Reactome: R-HSA-5357786 Reactome: R-HSA-5357905 Reactome: R-HSA-5675482 Reactome: R-HSA-69416 Reactome: R-HSA-75157 Reactome: R-HSA-75158 Reactome: R-HSA-9013957 Reactome: R-HSA-933543 Reactome: R-HSA-9693928
Alternative Antibody Names	Anti-Fas-Associated Death Domain Protein antibody Anti-Fas-Associating Death Domain-Containing Protein antibody Anti-Growth-Inhibiting Gene 3 Protein antibody Anti-Mediator Of Receptor Induced Toxicity antibody Anti-FADD antibody Anti-MORT1 antibody Anti-GIG3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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产品名称：Anti-FADD antibody (1-208) (STJ11100055)